Loss of Smell From COVID Can Last Many Months

TUESDAY, Feb. 23, 2021 (HealthDay News) — By now, most folks know that a loss of smell and taste are a hallmark of COVID-19 infection, but new research shows it can continue up to five months after the virus first strikes.

“It was apparent from the beginning of the pandemic that a significant percentage of people lost their capacity to smell,” said researcher Dr. Nicolas Dupre, director of neuromuscular and neurogenetic disease clinic at Laval University in Quebec. “This is quite common in many infectious diseases, but in COVID, the effect was much more important.”

In other viruses, smell and taste usually return after the sinuses are clear. But in COVID-19, the virus might penetrate the small area of the brain called the olfactory bulb, which is important for the recognition of smell, Dupre explained.

“The virus probably kills some of the cells in the olfactory bulb, and that’s why you have a long-lasting effect,” he said.

Losing your sense of smell can affect your daily life, Dupre said. And even when it returns, it can be different from before the virus, he said. In some people, the loss of smell might be permanent, but that’s not clear yet.

“We still think that in 80% of the people there’s not as a significant impact on their smell. So, most people will recover, but in a small percentage, it may be permanent, so this could be part of the long-term disability that we see in COVID,” Dupre said.

For the study, his team collected data on more than 800 health care workers who had COVID-19. The participants completed an online survey and home test to evaluate their sense of taste and smell about five months after diagnosis.

In all, 580 people lost their sense of smell, and 297 of them (51%) said they had not regained their sense of smell five months later. A home test found that 17% had persistent loss of smell.

Also, 527 participants lost their sense of taste during the initial illness. Of these, 38% said they had not regained their sense of taste five months later, and 9% had persistent loss of taste when evaluated with the home test, the researchers found.